Hidesaku Asakura Selected Research

Tranexamic Acid (AMCA)

1/2023	Effect of Anticoagulant/Antifibrinolytic Combination Therapy on Enhanced Fibrinolytic-Type Disseminated Intravascular Coagulation in End-of-Life Stage Solid Tumor Patients.
1/2022	Therapeutic Strategies for Disseminated Intravascular Coagulation Associated with Aortic Aneurysm.
9/2021	Blue Rubber Bleb Nevus Syndrome Complicated by Enhanced-Fibrinolytic-Type DIC: A Case Report.
1/2021	Management of disseminated intravascular coagulation associated with aortic aneurysm and vascular malformations.
10/2020	Consideration of Tranexamic Acid Administration to COVID-19 Patients.
4/2020	Coagulation and fibrinolytic features in AL amyloidosis with abnormal bleeding and usefulness of tranexamic acid.
12/2007	Successful combined use of tranexamic acid and unfractionated heparin for life-threatening bleeding associated with intravascular coagulation in a patient with chronic myelogenous leukemia in blast crisis.
11/2005	Kasabach-Merritt syndrome associated with giant liver hemangioma: the effect of combined therapy with danaparoid sodium and tranexamic acid.
9/2005	Effect of combined therapy of danaparoid sodium and tranexamic acid on chronic disseminated intravascular coagulation associated with abdominal aortic aneurysm.
10/2004	Beneficial effect of low-molecular-weight heparin against lipopolysaccharide-induced disseminated intravascular coagulation in rats is abolished by coadministration of tranexamic acid.

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Hidesaku Asakura Research Topics

Disease

55	Disseminated Intravascular Coagulation 05/2024 - 01/2002
25	Hemorrhage 12/2023 - 06/2002
20	Thrombosis (Thrombus) 05/2024 - 09/2003
8	COVID-19 01/2022 - 01/2020
7	Neoplasms (Cancer) 01/2023 - 03/2004
7	Sepsis (Septicemia) 01/2019 - 01/2004
6	Thrombocytopenia (Thrombopenia) 05/2024 - 09/2005
6	Aortic Aneurysm (Aneurysm, Aortic) 01/2022 - 09/2005
5	Acute Promyelocytic Leukemia 04/2016 - 09/2003
4	Infections 01/2020 - 01/2005
3	Thrombotic Microangiopathies 05/2024 - 05/2009
3	Inflammation (Inflammations) 08/2021 - 10/2006
3	Pulmonary Embolism 01/2021 - 07/2014
3	Hemophilia A (Haemophilia) 09/2019 - 01/2010
3	Venous Thrombosis (Deep-Vein Thrombosis) 03/2017 - 10/2011
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 02/2015 - 04/2004
3	Hematologic Neoplasms (Hematological Malignancy) 10/2014 - 12/2007
3	Abdominal Aortic Aneurysm 10/2009 - 09/2005
3	Graft vs Host Disease (Graft-Versus-Host Disease) 08/2006 - 12/2005
2	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 05/2024 - 05/2009
2	Thrombotic Thrombocytopenic Purpura 03/2023 - 02/2023
2	Cytokine Release Syndrome 10/2021 - 01/2021
2	Hemangioma (Angioma) 09/2021 - 11/2005
2	Disease Progression 01/2021 - 01/2020
2	Hyperkalemia 01/2021 - 02/2005
2	Immunoglobulin Light-chain Amyloidosis 04/2020 - 09/2012
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 01/2018
2	Liver Failure 01/2016 - 10/2011
2	Disease Susceptibility (Diathesis) 08/2015 - 01/2010
2	Myocardial Infarction 07/2014 - 09/2011
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 03/2014 - 08/2006
2	Lymphoma (Lymphomas) 03/2014 - 01/2006
2	Wounds and Injuries (Trauma) 06/2013 - 09/2003
2	Aneurysm (Aneurysms) 10/2009 - 01/2008
2	Leukemia 12/2007 - 12/2005
2	Bronchiolitis Obliterans Syndrome 02/2006 - 01/2006
2	Renal Cell Carcinoma (Grawitz Tumor) 02/2005 - 03/2004
1	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 05/2024
1	Amyloid Plaque 11/2023
1	Purpura 03/2023
1	Gastrointestinal Hemorrhage (Hematochezia) 03/2023
1	Epistaxis (Nosebleed) 03/2023
1	Death (Near-Death Experience) 01/2023
1	Venous Thromboembolism 01/2023
1	Multiple Organ Failure (MODS) 10/2021
1	Blue rubber bleb nevus syndrome 09/2021

Drug/Important Bio-Agent (IBA)

50	Dacarbazine (DIC)FDA LinkGeneric 02/2023 - 06/2002
13	Heparin (Liquaemin)FDA LinkGeneric 05/2024 - 06/2002
13	AnticoagulantsIBA 01/2023 - 01/2010
11	Tranexamic Acid (AMCA)FDA Link 01/2023 - 06/2004
11	LipopolysaccharidesIBA 01/2022 - 01/2002
10	Hemostatics (Antihemorrhagics)IBA 01/2022 - 01/2002
9	Thromboplastin (Tissue Factor)IBA 08/2021 - 01/2002
8	AntithrombinsIBA 01/2021 - 09/2012
5	Antifibrinolytic Agents (Antifibrinolytics)IBA 01/2023 - 09/2005
5	fibrin fragment D (D-dimer)IBA 03/2022 - 05/2004
4	FibrinIBA 08/2021 - 10/2004
4	ThrombomodulinIBA 01/2019 - 03/2014
3	VaccinesIBA 05/2024 - 01/2022
3	Fibrinogen (Factor I)FDA Link 03/2022 - 04/2003
3	nafamostatIBA 01/2022 - 01/2020
3	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2022 - 10/2004
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2021 - 10/2002
3	Factor X (Stuart Factor)IBA 01/2020 - 09/2012
3	CytokinesIBA 10/2008 - 09/2006
3	antithrombin III-protease complexIBA 10/2006 - 01/2002
3	Endothelins (Endothelin)IBA 04/2005 - 10/2002
2	idarucizumabIBA 12/2023 - 06/2020
2	Factor XIII (Coagulation Factor XIII)IBA 02/2023 - 06/2020
2	Thrombin FDA Link 07/2021 - 11/2016
2	NG-Nitroarginine Methyl Ester (L-NAME)IBA 07/2021 - 01/2004
2	prothrombin complex concentrates (PPSB)IBA 01/2020 - 01/2010
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2018 - 09/2011
2	RivaroxabanIBA 11/2017 - 07/2014
2	Warfarin (Coumadin)FDA LinkGeneric 11/2017 - 10/2011
2	Blood Coagulation Factors (Coagulation Factor)IBA 01/2015 - 01/2010
2	Factor VII (Proconvertin)IBA 03/2012 - 01/2002
2	Annexin A2 (Annexin II)IBA 10/2009 - 01/2008
2	Inosine Triphosphate (ITP)IBA 05/2009 - 09/2006
2	danaparoid (Orgaran)FDA Link 11/2005 - 09/2005
1	Factor V (Coagulation Factor V)IBA 12/2023
1	GoldIBA 11/2023
1	von Willebrand FactorIBA 03/2023
1	caplacizumabIBA 03/2023
1	Alanine Transaminase (SGPT)IBA 03/2023
1	thiamine triphosphorate (TTP)IBA 02/2023
1	HaptoglobinsIBA 02/2023
1	COVID-19 VaccinesIBA 03/2022
1	Platelet Factor 4IBA 03/2022
1	ImmunosorbentsIBA 03/2022
1	AntibodiesIBA 03/2022
1	EnzymesIBA 03/2022
1	Erythropoietin FDA Link 01/2022
1	apixabanIBA 09/2021
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2021

Therapy/Procedure

15	Therapeutics 01/2023 - 09/2005
5	Drug Therapy (Chemotherapy) 01/2021 - 04/2004
3	Bone Marrow Transplantation (Transplantation, Bone Marrow) 12/2007 - 04/2004
3	Stem Cell Transplantation 12/2005 - 03/2004
1	Sclerotherapy 09/2021